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oneskin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free, 250 mL / 8.45 oz

oneskin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free, 250 mL / 8.45 oz

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 Peptide™.

⦁ Improves skin texture, appearance, and hydration

⦁ Strengthens the skin barrier by up to +41%

⦁ Dermatologist tested, fragrance-free, safe for sensitive skin

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Regular price $88.99
Regular price $88.99 Sale price $105.00
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oneskin BODY OS-01 Peptide Topical Supplement & Skin Longevity Age Reversal Moisturizer | Safe for Sensitive Skin, Fragrance-Free, 250 mL / 8.45 oz
Regular price $88.99
Regular price $88.99 Sale price $105.00
SAVE 15% Sold out

Clean + Safe Ingredients

Our products are non-comedogenic (non pore-clogging), 100% free from fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives, and solvents. We prioritize the use of key ingredients that ensure a safe and effective formulation, delivering the best results for your skin needs.

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture
Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.

Deep hydration
Replenishes and locks in hydration to keep skin soft, plump, and nourished.

Barrier support
Fortifies the skin barrier to protect against daily stressors and moisture loss.

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

The proof is in the pictures

CLINICAL DATA

Visible results, scientifically validated

93%

of participants reported improved hydration

72%

of participants reported improved appearance

70%

of participants reported improved texture

41%+

Improvement in skin barrier function was measured

ONESKIN LONGEVITY SCIENCE™

The Science Behind OS-01 BODY

Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.

Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

5 active ingredients complement the OS-01 peptide





5 active ingredients complement the OS-01 peptide

Tremella Fuciformis Sporocarp Mushroom extract

This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.

Sulforaphane

Found in Lepidium Sativum Sprout Extract, this antioxidant has potent antimicrobial and anti-inflammatory properties.

Genistein

A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.

Ceramides

Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

Ceramides

Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

Saccharide isomerate

A prebiotic shown to support the healthy bacteria on skin.

Saccharide isomerate

A prebiotic shown to support the healthy bacteria on skin.


Note: Due to the natural oils used in our formulas, the scent of the product may vary.

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily
  •  

    How it works

    Powered by the OS-01 Senescence Blocking Peptide™

    The first and only peptide scientifically proven to reverse skin’s biological age.

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

  • Finally Works!

    My skin feels firmer and hydrated after just a few uses. Love it!

    Lauren T.

  • Smooth & Plump

    Absorbs quickly and makes my skin look so much better.

    Marcus P.

  • Gentle & Effective

    Locks in moisture without irritation—perfect for sensitive skin.

    Danielle W.

    FAQs

    What is OS-01 BODY?

    OS-01 BODY is a topical skin supplement designed to support healthier, smoother-looking skin.

    How does it work?

    It helps improve the appearance of aging skin by supporting skin renewal and hydration.

    Who should use this product?

    It’s ideal for anyone looking to improve dry, aging, or crepey skin.

    How often should I use it?

    Apply once or twice daily for best results.

    Can I use it on sensitive skin?

    Yes, the formula is designed to be gentle, but a patch test is recommended.