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    CELEBRATING 10 YEARS

    A decade of longevity science. A new standard for your skin.

    Powered by our proprietary OS-01TMpeptide to target cellular aging at the source—for skin that looks and acts younger.

  •  

    CELEBRATING 10 YEARS

    A decade of longevity science. A new standard for your skin.

    Powered by our proprietary OS-01TMpeptide to target cellular aging at the source—for skin that looks and acts younger.

OUR APPROACH

Led by science, not hype

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

Ongoing clinical studies

Conducted by independent, third-party research organizations.

Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Peer-reviewed publications

The gold standard for scientific research and in skin care.

    BENEFITS

    Nourishing body moisturizer and targeted treatment for thin, crepey skin

    Smooth texture
    Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.

    Deep hydration
    Replenishes and locks in hydration to keep skin soft, plump, and nourished.

    Barrier support
    Fortifies the skin barrier to protect against daily stressors and moisture loss.

    OUR BREAKTHROUGH PEPTIDE

    OS-01: the new standard in peptide technology

    Think of OS-01 as a reset button for your skin, helping clear away the senescent cells that cause wrinkles, hyperpigmentation, and crepiness. As the first peptide scientifically proven to reduce cellular senescence in the skin, OS-01 does what other peptides can’t.

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    6 visible signs of senescence

    Lines and wrinkles

    Caused by a decline in collagen and elastin production.

    Rough texture

    Compromised skin cell renewal leaves a dry, uneven surface.

    Loss of elasticity

    Decreased elastin also contributes to lack of firmness.

    Loss of volume

    Linked to a decrease in hyaluronic acid, collagen, and elastin.

    Uneven skin tone

    Irregular melanin production leads to hyperpigmentation.

    Thinning skin

    Slower cell turnover contributes to a weakened skin barrier.

    5-STAR REVIEWS

    See why customers love OS-01 BODY

    “The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

    "The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


    "I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

    The proof is in the pictures

    CLINICAL DATA

    Visible results, scientifically validated

    93%

    of participants reported improved hydration

    72%

    of participants reported improved appearance

    70%

    of participants reported improved texture

    41%+

    Improvement in skin barrier function was measured

    Getting started with OS-01 BODY

    Follow these easy steps for optimal results

    • Apply to arms, legs, chest, back, and stomach
    • Massage until absorbed
    • Use 2 times daily
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    5 active ingredients complement the OS-01 peptide





    5 active ingredients complement the OS-01 peptide

    Tremella Fuciformis Sporocarp Mushroom extract

    This antioxidant-rich natural extract reduces UV-induced water and collagen loss induced by uv damage.

    Sulforaphane

    Found in Lepidium Sativum Sprout Extract, this antioxidant has potent antimicrobial and anti-inflammatory properties.

    Genistein

    A powerful anti-inflammatory antioxidant that helps prevent and fade photoaging and dark spots.

    Ceramides

    Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

    Ceramides

    Supports skin’s natural lipid barrier to protect, boost moisture retention and repair dry and sensitive skin.

    Saccharide isomerate

    A prebiotic shown to support the healthy bacteria on skin.

    Saccharide isomerate

    A prebiotic shown to support the healthy bacteria on skin.


    Note: Due to the natural oils used in our formulas, the scent of the product may vary.

    ONESKIN LONGEVITY SCIENCE™

    The Science Behind OS-01 BODY

    Your skin is your largest organ and plays a vital role in your overall health as you age. Over time, it becomes thinner, more fragile, and less effective at protecting you from external aggressors. While most skincare focuses on the face, the other 97% of your skin is just as essential for longevity and well-being. OS-01 BODY is designed to strengthen your skin barrier from the neck down, keeping it resilient.

    To evaluate OS-01 BODY’s effectiveness, our scientists measured epidermal thickness—a key indicator of barrier strength—using human skin samples in the lab. Results showed a 40% increase in epidermal thickness compared to untreated skin. This aligns with clinical findings demonstrating OS-01 BODY enhances skin barrier function by up to 41.49%.

    Shown in lab studies on ex vivo human skin samples by measuring epidermal thickness of histology images. Skin treated with OS-01 BODY displayed a significant average increase of +40% compared to skin with no treatment. Data was measured in triplicate.

    FAQs

    How long before I see results?

    Many users notice smoother skin within a few weeks of consistent use.

    Is it greasy or heavy?

    No, it absorbs quickly and leaves a lightweight, non-greasy feel.

    Can I use it with other skincare products?

    Yes, it can be used alongside your regular skincare routine.

    Where can I apply it?

    Use it on areas like arms, legs, neck, and other areas needing hydration.

    Does it have fragrance?

    It’s formulated to be gentle and suitable for most skin types.